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TESTOSTERONE
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| StockNo |
Product description |
| EB0280-445-11 |
TESTOSTERONE
PROPIONATE AMPOULE 50 MG/1 ML (5%) |
| EB0280-445-15 |
TESTOSTERONE
PROPIONATE AMPOULE 10 MG/1 ML (1%) |
| EB0280-445-16 |
TESTOSTERONE
PROPIONATE AMPOULE 15 MG/1 ML (2.5%) |
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- COMPOSITION:
Testosterone propionate 10 mg/1 ml, 25 mg/1 ml and
50 mg/1 ml in one ampoule
ACTION:
Male sexual hormone with pronounced, mainly androgenic action,
possessing the biological and therapeutic properties of the natural
hormone. Unlike it, however, it is absorbed more slowly and is more
stable in the body. In a healthy male organism, androgens are formed
by the testes and adrenal cortex. It is normally produced in women
in small physiological quantities. In addition to the specific
action that determines the sexual characteristics of the individual,
it also has a general anabolic action, manifested in enhancement of
protein synthesis. Under the effect of testosterone, body weight
increases and urea excretion is reduced. High doses suppress the
production of hypophyseal gonadotropin, while low doses stimulate
it. It has an antitumor effect on mammary gland metastases.
INDICATIONS:
Impotence, sterility, deficiency phenomena after castration of
males; for provoking sexual maturing in eunuchoidism, congenital
underdevelopment of sexual glands and in the absence of secondary
sexual characteristics; acromegaly; cryptorchism; adiposogenital
dystrophy; hypogenitalism and male climacteric. Rarely in
hormone-dependent cancers of mammary glands with bone metastases.
CONTRAINDICATIONS:
Cancer of prostate; in sharply mahifested atherosclerosis,
myocardial infarction, cardiac insufficiency. In females with
hypercalcemia, metastases in bones from breast cancer. |
SIDE EFFECTS:
Most often - retention of water and salts in the body, which leads
to formation of edemas, very risky in patients with cardiac
decompensation and congestive phenomena in the extremities (favours
the advance of thrombophlebitis). The occurrence of priapism is a
manifestation of excessive dosage, necessitating a temporary
discontinuation of the treatment. In patients with liver lesiaons,
it can provoke icterus of a cholostatic type.
DRUG INTERACTIONS:
Edemas are formed during parallel administration with ACTH.
Testosteron enhances the action of coumarin anticoagulants, insulin,
metformine, sulfonylurea antidiabetic agents. Barbiturates decrease
the action of testosterone.
DOSAGE AND ADMINISTRATION:
It is injected in the upper-outer quadrant of the gluteal muscle,
according to physician's prescription and under physician's control.
The daily dose is 5-10-25 mg, injected in a rhythm: every day to 2-3
times weekly. The high doses are used in underdeveloped sexual
glands and acromegaly (from the beginning until clinical
improvement). In impotence the male climacteric (as well as rarely
in hyperthrophy of the prostate), the doses are lower: 0.01-0.025
respectively, daily or every 2-3 days. Very high doses are used in
oncological practice for females: 0.05 daily for weeks.
MEDICINAL FORM AND PACKAGE:
Packages with 10 and 50 ampoules of 10 mg/1 ml (1 %), 25 mg/1 ml
(2.5 %) and 50 mg/1 ml (5 %).
STORAGE:
At moderate temperature (15-30° C) in a place protected from light.
If crystals appear, the ampoule is heated in water bath until they
dissolve completely and the solution becomes clear.
EXPIRY:
5 (five) years.
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